l-carnitine alternative medicine review Deficiency and Therapeutic Uses Acetyl L-Carnitine

There is some indirect evidence to suggest that excess lysine in the diet may increase endogenous L-carnitine synthesis

Targeting of Fn14 prevents cancer-induced cachexia and prolongs survival

L- amino acids are essential for protein synthesis and energy production, and mammals (including humans) synthesize amino acids almost exclusively in the L- configuration.75 In supplements, L- or D- may be more informed by bioavailability, as the body may better absorb the L form of one amino acid or the D form of another

We discuss the failure of previously tested antioxidants, neuroprotective agents, anticonvulsants and antidepressants as therapeutic or preventative strategies, and suggest individualized, mechanism-based therapeutic options for CIPNP associated with each of the three main drug groups